Short-term effects of antipsychotic treatment on cerebral function in drug-naive first-episode schizophrenia revealed by rfMRI
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چکیده
(left panel) and rendered images (right panel) showing results of the ALFF analysis. Upper: compared with normal controls, patients at baseline showed significantly decreased (blue) ALFF only in bilateral ventral medial frontal cortex (P < 0.05 corrected). Middle: compared with baseline, patients after six weeks showed significantly increased (red) ALFF mainly in bilateral prefrontal and parietal lobes (P < 0.05 corrected). Lower: compared with controls, patients after six weeks showed significantly increased (red) ALFF in right caudate and left putamen (P < 0.05 corrected). Short-term effects of antipsychotic treatment on cerebral function in drug-naive first-episode schizophrenia revealed by rfMRI
منابع مشابه
Short-term effects of antipsychotic treatment on cerebral function in drug-naive first-episode schizophrenia revealed by "resting state" functional magnetic resonance imaging.
CONTEXT Most of what we know about antipsychotic drug effects is at the receptor level, distal from the neural system effects that mediate their clinical efficacy. Studying cerebral function in antipsychotic-naive patients with schizophrenia before and after pharmacotherapy can enhance understanding of the therapeutic mechanisms of these clinically effective treatments. OBJECTIVE To examine a...
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متن کاملCNS Drugs 2009;
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تاریخ انتشار 2009